![]() ![]() ↑ Bursill D, Taylor WJ, Terkeltaub R, Kuwabara M, Merriman TR, Grainger R, Pineda C, Louthrenoo W, Edwards NL, Andrés M, Vargas-Santos AB, Roddy E, Pascart T, Lin CT, Perez-Ruiz F, Tedeschi SK, Kim SC, Harrold LR, McCarthy G, Kumar N, Chapman PT, Tausche AK, Vazquez-Mellado J, Gutierrez M, da Rocha Castelar-Pinheiro G, Richette P, Pascual E, Fisher MC, Burgos-Vargas R, Robinson PC, Singh JA, Jansen TL, Saag KG, Slot O, Uhlig T, Solomon DH, Keenan RT, Scire CA, Biernat-Kaluza E, Dehlin M, Nuki G, Schlesinger N, Janssen M, Stamp LK, Sivera F, Reginato AM, Jacobsson L, Lioté F, Ea HK, Rosenthal A, Bardin T, Choi HK, Hershfield MS, Czegley C, Choi SJ, Dalbeth N (March 2019)."Prevalence of gout and hyperuricemia in the US general population: the National Health and Nutrition Examination Survey 2007-2008". ↑ Zhu Y, Pandya BJ, Choi HK (October 2011)."A concise history of gout and hyperuricemia and their treatment". Till today the colchicine therapy is used to prevent gout flares and played a huge role in the management of patients with Gout. The most noticeable user for the colchicine was Benjamin Franklin. Then due to any reason, this was out of use for hundreds of years before re-discovering it for use by an Australian physician Baron Anton de Stock in 1700. Bloodletting is also one of the ancient techniques used at that time.Īlthough colchicine was used in ancient times for more than 2000 years it was first used for the treatment of Gout Alexander of Tralles in around 600 AD. He conducted some great experiments and eye-opening research where he demonstrated the relation between high levels of uric acid in the bloodstream and the development of gout.ĭifferent treatment and management theories are studied and implemented to manage the Gout over years but the Early treatment options that came from Hippocrates included minimal water and counterirritation that is basically scorching the veins near the joint affected. The next remarkable contribution to the study of gout was made by Alfred Baring Garrod. This was later identified as urate crystals by a Swedish scientist named "Carl Scheele". The tophi that are uric acid crystal deposits those were fist identified, studied, and described these as tiny needle-like particles under the microscope by the famous scientist " Anton Von Leeuwenhoek". He also helps in explaining and differentiating gout from the other diseases related to different forms of arthritis. In the seventeenth century the scientist " Thomas Sydenham" was the first person to study the aspects of Gout disease in terms of Acute or chronic aspects. In English "gout", In French " goutte" and in the Italian language it means " gotta" and in German named as "gicht" Till day the variation of terms is seen in different languages all over the world. The term is usually derived from the Latin word gutta or drop. The first person to name the disease was " Randolph of Bocking" in the early 1200s. Which later on given the name of Uric acid in further studies. After a century later there is another scientist named Cappadocian gave a proposal that the gout disease is caused by the toxin in the blood. Although it was first recognized by Egyptians the first clinical description of the disease came from Hippocrates ( 460-370). The scientist has a lot to offer regarding this chronic and debilitating disease. Out of them, the males are affected the most. This is one of the most studied diseases do far with more than millions of people still suffering from the disease until today. Gout was first identified by Egyptians around 2640 BC. Antoine van Leeuwenhoek contributed to the field by describing the appearance of uric acid crystals in 1679., (1632-1723)._Natuurkundige_te_Delft_Rijksmuseum_SK-A-957.jpeg ![]()
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